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Writer's pictureDemian Gitnacht, MD, MPH, FAAFP

Mushroom Therapy: Lion's Mane and Reishi for Mental Health

Mushrooms have been popping up everywhere – from trendy health cafes to cutting-edge research labs – and for good reason. Beyond their culinary appeal, certain mushrooms are earning recognition for their potential to boost mental health and emotional well-being. At Kalea Wellness, where we focus on therapies like ketamine-assisted psychotherapy and holistic approaches to sleep and lifestyle management, we believe nature can play a profound role in healing. Lion's Mane and Reishi are two mushrooms that have captured attention for their unique benefits. Whether you are looking to sharpen your focus or find relief from stress, these fungi might just deserve a spot in your wellness routine.


Lion's Mane mushrooms, scientifically known as Hericium erinaceus, look like tiny white pom-poms or a lion’s shaggy mane, hence the name. These mushrooms are packed with compounds that support brain health. Lion's Mane is known to promote nerve growth factor, which essentially helps neurons repair and regenerate. This makes it a potential ally for improving memory, focus, and even reducing symptoms of anxiety and depression. Some studies suggest it may even protect against age-related cognitive decline. Think of it as a renovation crew for your brain, patching up old connections and wiring new ones.


Lion's Mane
Lion's Mane mushrooms (Hericium erinaceus)

Reishi mushrooms, or Ganoderma lucidum, on the other hand, are often called the “mushroom of immortality.” While they probably will not make you live forever, they do seem to help with stress management, sleep quality, and overall mood stabilization. Reishi is like a soothing cup of tea for your nervous system. It has adaptogenic properties, meaning it helps your body adapt to stress and restores balance. For those feeling constantly overwhelmed, Reishi might be the perfect evening ritual to calm the mind and prepare for restorative sleep. It is also known for its immune-boosting effects, which means it does double duty – supporting both mental and physical health.


Reishi mushroom (Ganoderma lucidum)
Reishi mushrooms (Ganoderma lucidum)

When it comes to dosing, Lion's Mane and Reishi can be found in capsules, powders, or tinctures, making them easy to add to your routine. Lion's Mane is often taken in doses ranging from 500 milligrams to 3,000 milligrams per day, typically in the morning to support focus and energy. Reishi, on the other hand, is usually taken at night in doses of 1,000 to 3,000 milligrams, as it promotes relaxation and sleep. It is important to read product labels carefully, as dosing can vary depending on the formulation.


So, who should take these mushrooms? Lion's Mane may be best for individuals looking to enhance focus, memory, or mental clarity – perhaps someone navigating stressful workdays or dealing with mild cognitive concerns. Reishi might be a better fit for those struggling with anxiety, insomnia, or burnout and needing a little extra help unwinding at the end of the day. For those undergoing ketamine-assisted psychotherapy, these mushrooms may complement the process beautifully. Lion's Mane could support neuroplasticity – the brain's ability to form new connections – while Reishi may enhance relaxation and integration of the therapeutic experience.


Both mushrooms can be found at health food stores, online retailers, or even farmer’s markets if you are lucky. To ensure you are getting the right product, look for organic certifications and third-party testing to verify purity and potency. Labels should specify that the product contains extracts from the fruiting body rather than just mycelium, as the fruiting body contains the most active compounds. Reliable resources include trusted supplement brands, natural health stores, and reputable online marketplaces. Reading customer reviews and consulting your healthcare provider can also help you make an informed decision. Mushroom coffee blends and teas are gaining popularity and can be an enjoyable way to incorporate these fungi into your daily routine.


While these mushrooms are generally safe, it is always a good idea to check with your healthcare provider before starting any new supplement. Some people may experience mild digestive upset or allergic reactions. Reishi, in particular, may thin the blood, so it is not recommended for individuals on anticoagulant medications or those undergoing surgery. Pregnant or breastfeeding women should also exercise caution and consult their doctor.

In summary, Lion's Mane and Reishi mushrooms are two powerful tools for supporting mental health, improving focus, and reducing stress. Whether you need a brain boost or a calming companion, these mushrooms offer natural, gentle support that may complement therapies like ketamine-assisted psychotherapy. So, if you are ready to step into the mushroom kingdom, consider giving these fungi a try. After all, who knew that mushrooms could double as brain boosters and not just something hiding in the back of your fridge?


Stay curious, stay healthy, and maybe let these mushrooms remind you that growth – even for your neurons – can come from the most unexpected places.


Lion's Mane supplements

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